Pentobarbital will decrease the level or effect of aprepitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of zonisamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of cevimeline by affecting hepatic/intestinal enzy... https://top100bookmark.com/story20473092/tutto-ci%C3%B2-che-riguarda-what-is-nembutal-pentobarbital