Below, we show that conolidine, a organic analgesic alkaloid used in conventional Chinese medication, targets ACKR3, therefore supplying further evidence of the correlation concerning ACKR3 and soreness modulation and opening option therapeutic avenues for the remedy of Long-term pain. We shown that, in contrast to classical opioid receptors, ACKR3 https://www.proleviate.com/post/conolidine-proleviate-for-pain-muscle-joint-ankle-relief