OBJECTIVES/GOALS: Chronic or new symptoms after infection with severe-acute-respiratory-coronavirus-2 (SARS-CoV-2) has been termed post-acute sequelae of Covid-19 (PASC) or Long Covid. Our objective is to present results from COVID-OUT. a phase 3 double-blind. randomized controlled trial of early outpatient treatment of Covid-19 with repurposed medications. https://www.rawafricaonline.com/