As revealed in Table I and Fig. 2, AS-IV leads to apoptosis primarily by the mitochondrial-dependent intrinsic pathway plus the death receptor-dependent extrinsic pathway. The intrinsic pathway leads to the release of cytochrome c Induced accumulation of Nrf2 in the nucleus, synthesized antioxidant enzymes as a result of detrimental regulation https://samuelv000jvg3.blog2news.com/profile